How to change the value of object in React [duplicate]

I want to change the clicked:false on true. I want to do that in react. How can I do that with Spread operator?
And how can I do that properly?

let questions = [
        title: "Was möchte ich lernen?",
        letters: ["a", "b", "c", "d"],
        variants: ["Deutsch", "English", "Franzosisch", "Turkisch"],
        clicked: false
 const [result, setResult] = useState<any>(questions)
<button onClick={()=>setResult(...questions)}></button>