How to force column to be in array if it matches the whole thing?

I have the following MySQL query:

SELECT tbPacientesComunicacao.id 
FROM tbPacientesComunicacao 
WHERE tbPacientesComunicacao.idRefUser = 1 
   AND tbPacientesComunicacao.idRefPaciente = 4
   AND tbPacientesComunicacao.id IN (
     SELECT idRefComunicacao 
     FROM tbPacientesComunicacaoDestinatarios 
     WHERE idRefUser IN (2,8)
   );

The issue is that MySQL returns the ID if either 2 or 8 matches… how can I say hey only return the id if both numbers (2 and 8) matches?

Table tbPacientesComunicacao

Table tbPacientesComunicacaoDestinatarios

When a new record is being inserted, I have to check if that record doesn’t match any of the communications already in the database. So I pass the user IDs in an array(5,8) then I have to check it somehow if there is something in the database the matches EXACTLY this combination of UserIDs, in this test it shouldn’t match because I have 5 and 7 not 5 and 8 but using “in” it says it was matched because it found at least one of them… how can I determine that only matches if all numbers in the array matches the table userID?