SNP leader Alex Salmond will set out his case for a second term in government by saying only his party can get Scotland through tough times.
The first minister will tell the SNP conference that Scotland needs independence to escape the “Westminster straitjacket” of cuts.
Mr Salmond’s speech in Perth comes ahead of Chancellor George Osborne’s spending review on Wednesday.
The SNP says that may result in £1bn of cuts from next year’s Scottish budget.
The party dropped its plan for an independence referendum bill because of a lack of political support and is now seeking to make it a central issue of next May’s Scottish parliament election.
Mr Salmond will tell delegates: “Either Scotland stays in the Westminster straitjacket of low growth, public sector cutbacks and blighted futures – or we take responsibility and change our circumstances for the better.”
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