Americans Peter Diamond and Dale Mortensen, and British-Cypriot Christopher Pissarides, have won the 2010 Nobel economics prize.
They were honoured for work on how unemployment, job vacancies and wages are affected by regulation and policy.
The Royal Swedish Academy of Sciences praised their work on why unemployment stays high in times of many vacancies.
The 10m Swedish kronor ($1.5m) economics prize was set up by the Royal Swedish Academy of Sciences in 1968.
Mr Diamond, 70, is an economist at the Massachusetts Institute of Technology and an authority on social security, pensions and taxation.
US President Barack Obama has nominated him to become a member of the US Federal Reserve.
Mr Mortensen, 71, is an economics professor at Northwestern University in Evanston, Illinois, and Mr Pissarides, 62, is a professor at the London School of Economics.
Professor Pissarides said he received the news with “a mixture of surprise and happiness, general satisfaction”.
“This is prize is so great you don’t believe that you will get it even after you’ve got it,” he said.
Among other subjects, their research looked into why unemployment remains high even at times when there are large number of job vacancies.
Their general conclusion is that searching for jobs can take up so much time and resources that economies can have both a high jobless levels and high vacancy rates simultaneously.
The citation from the Swedish academy said: “The Laureates’ models help us understand the ways in which unemployment, job vacancies, and wages are affected by regulation and economic policy.
“This may refer to benefit levels in unemployment insurance or rules in regard to hiring and firing. One conclusion is that more generous unemployment benefits give rise to higher unemployment and longer search times.”
Last year’s economics prize was won by Americans Oliver Williamson and Elinor Ostrom – the first woman to receive the award – for research on economic governance.
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