Weight ‘key’ in kidney transplant

Organ transplant box

Matching up the weight of donors and recipients boosts success in kidney transplants, suggests French research.

A study of over 1,000 transplant patients found those receiving a small kidney in proportion to their weight were more at risk of complications.

In the Journal of the American Society of Nephrology, the researchers said the findings would give surgeons a new chance to improve long-term survival.

But a UK expert warned a donor shortage would limit weight-based matches.

The team followed the transplant patients for an average of six years after their operation.

Using a calculation based on the weight of the donor kidney, and the weight of the person having the transplant, they found that those receiving a small kidney for their size had more complications.

These included high blood pressure, kidney scarring, and a 55% increased risk of transplant failure two years after the operation.

Study leader Professor Jean Paul Soulillou, from the French National Institute of Health and Medical Research, said from a clinical point of view the impact of the finding was similar to when researchers identified markers to enable tissue type to be matched to reduce the risk of rejection.

"This information is potentially useful for thousands of transplants and provides a new opportunity to improve long-term graft survival," he added.

Living donors

The vast majority of the transplants in the study were done with organs from dead donors.

In the UK, living donor kidney transplants are on the rise – with 927 carried out in 2008-2009 representing more than one in three of all kidney transplants.

Keith Rigg, consultant transplant surgeon in Nottingham and president of the British Transplantation Society, said doctors already consider body weight where possible in the case of transplants done with living donors.

"The interesting thing they have done here is to actually weigh the kidney.

"But the problem is when you have a scarce resource of kidneys, taking account of weight would complicate what is already a complex allocation system.

"In the long term, it is still better to have a transplant than remain on dialysis."

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Over the Rainbow winner Danielle steps into Dorothy’s ruby slippers

Sophie Evans and Danielle Hope

An 18-year-old student has won the BBC’s Over the Rainbow show and the right to wear Dorothy’s ruby slippers in a new Wizard of Oz production.

Danielle Hope, from Greater Manchester, emerged as the audience’s favourite Dorothy after two months of singing before the nation and judging panel.

She was joined in the final by 17-year-old Sophie Evans, from south Wales.

Hope will lead the cast in an Andrew Lloyd Webber West End production due to be staged next year.

In addition to finding a leading lady, the talent show also found a new four-legged star to play Dorothy’s pet dog Toto.

He was revealed as Mini Schnauzer Dave or "Dangerous Dave", as he is known to his owner.

‘Act from the soul’

After she was declared the winner by host Graham Norton, Hope smiled and hugged fellow finalist Evans.

She laughed off Norton’s remark that she was now a West End star and thanked everyone involved, including the audience, backstage crew, judging panel and the other girls.

"All I can say is thank you but it really does come from in here," she said. "It feels like not enough but I am just so grateful. We all are for this amazing opportunity."

Lloyd Webber said he was "really pleased" with the result and the nation had never been wrong yet.

"You’re the most fantastic, talented kid with a huge future ahead," he said.

"Now the hard work starts but my goodness me, you can act from the soul and that is something that’s very special."

The show ended with Hope’s rendition of Over the Rainbow, the hit song from the Wizard of Oz.

Hope, from Urmston, is a full-time student and keen dancer.

There were initially 20 contestants hoping to walk down the yellow brick road but they were whittled down to just 11 for the first show.

Hope was one of three to make it through to the final, with 22-year-old Londoner Lauren Samuels knocked out at the end of the first live show after receiving the lowest number of viewers’ votes.

This was the fourth Lloyd Webber TV talent search, following on from How Do You Solve A Problem Like Maria?, Any Dream Will Do and I’d Do Anything.

In addition to Lloyd Webber, the judging panel consisted of actress Sheila Hancock, singer Charlotte Church and actor John Partridge.

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Lawnmower man breaks speed record

Don Wales

A British lawnmower has cut the world land speed record by reaching a new top speed of more than 86mph.

Rider Don Wales took the petrol driven mower into the record books at Pendine Sands, in west Wales.

The previous lawnmower land speed record was 80.792mph (130.022km/h) set in America – Mr Wales was recorded as reaching 86.069mph.

His team are now due to return to the same spot on Sunday in a bid to break the 100mph barrier.

Those making a bid for the record must drive over a measured mile in one direction and return within an hour.

Any of the motorised grass cutters taking part must also be built primarily from lawnmower parts.

Mr Wales’s grandfather was Sir Malcolm Campbell who broke the world land speed record, in a car, at the same venue in 1924.

The record attempt, named Project RunningBlade, has been led by the National Motor Museum in Beaulieu, Hampshire.

American Bob Cleveland set the previous land speed record on a lawn-mower at Bonneville Salt Flats, Utah, and was present at Saturday’s run in Wales.

The record attempt also raised funds for Great Ormond Street Hospital for Sick Children and Wessex Heartbeat.

This article is from the BBC News website. © British Broadcasting Corporation, The BBC is not responsible for the content of external internet sites.

Man dies in ‘motiveless’ shooting

Shooting scene at Harrow Road

A man has died in what is believed to be a drive-by shooting in west London.

Metropolitan Police officers found the wounded man towards the southern end of Harrow Road just after 1215 BST on Saturday.

The victim, in his 20s, was treated at the scene but died from his injuries within an hour. He has not yet been named.

The fatal shot was fired from a dark-coloured car which was travelling north on Harrow Road, police said.

No-one has been arrested over the shooting. A murder investigation has started.

A post-mortem examination will be held in due course.

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Champions League glory for Inter

Champions League winners Inter Milan

Jose Mourinho wrote his name into the history books as Diego Milito inspired Inter Milan to Champions League glory against Bayern Munich at the Bernabeu.

Milito set Inter on their way against the run of play with a clipped finish.

And he wrapped up a win built on the foundations of a solid defence with a solo effort that saw Inter become the first Italian side to win the Treble.

It means Mourinho, who won the cup with Porto in 2004, becomes the third man in history to win it with two clubs.

He joins Ernst Happel and Ottmar Hitzfeld in earning that remarkable accolade – at the age of only 47 – and, in doing so, ends a wait of more than 45 years for the Nerazzurri to regain Europe’s top prize.

That he did so by overcoming his former mentor Louis van Gaal, with whom he worked at Barcelona, in the process only served to complete the ultimate season of personal vindication for the Portuguese.

If reports are to be believed, it is a triumph that will earn Mourinho the manager’s position at arguably the world’s biggest club in Real Madrid this summer.

How fitting, then, that this triumph was earned at Real’s magnificent Bernabeu stadium – and as Mourinho waved to the Inter fans after watching his side lift the trophy, it looked every inch a wave goodbye and confirmation this will prove the denouement of his Inter career.

As for the match itself, while it might not have been one for the purists, as an occasion it was spectacular.

The decision to switch the match to a Saturday evening was fully justified as both sets of supporters rocked the Bernabeu from the first minute to the last.

And on the field, the fare was no less enthralling.

The build-up had been dominated by Van Gaal’s and Robbens’ accusations that Mourinho is a defensive tactician in the build-up – but if their hope was that such taunts would prompt a more ambitious approach from the Italian champions, they were to be disappointed.

The first couple of minutes aside, when Inter hinted at an expansive approach, the Italian side’s tactics were clearly to stay strong defensively and pounce on the counter attack.

For a long time, though, it played right into Bayern’s hands. With Robben giving left-back Christian Chivu a torrid time and Mark van Bommel pulling the strings in midfield, the Germans almost completely dominated.

Playing with an air of expression and invention, Bayern probed the Inter backline time and again. Robben beat Chivu down the right to set up Ivica Olic, the Croatian slamming wide, Hamit Altintop saw a right-foot shot deflected wide and Robben then skewed wide when well placed 18 yards out.

At the other end, Schneider saw a deflected 40-yard free-kick beaten away by Bayern keeper Hans Jorg Butt and Esteban Cambiasso had a firm volley blocked, but Inter’s attacking personnel were largely anonymous in the face of the Germans’ control.

Then, on 34 minutes, came Inter’s ambush, Milito nodding Inter keeper Julio Cesar’s long clearance down to Schneider and then dashing onto the Dutchman’s smart return pass to clip home a delightful finish.

Mourinho’s muted celebrations might have betrayed his awareness it was a lead his side barely deserved, though it could – and should – have been 2-0 moments before the break when Schneider shot tamely from Milito’s lay-off and Butt palmed away his effort from 16 yards out.

Still, having watch Inter repel pass-masters Barcelona with 10 men in the semi-final, Bayern boss Van Gaal will have been all too mindful of the Italians’ ability to defend a lead and he sent his team out flying in the second half.

Jose Mourinho

Just moments after kick-off, the German champions should have been level, Thomas Mueller failing to connect smartly enough with a sliding finish with just the keeper to beat, allowing Cesar to beat his shot away.

It was a miss he was almost made to rue within minutes as Milito burst down Bayern’s left, cut the ball back to Pandev, only for Butt to brilliantly tip the Macedonian’s clipped effort past the post.

Predictably, though, the pattern for the second half had been set – Bayern controlling possession and Inter sitting deep and breaking.

Robben remained far and away Bayern’s most potent weapon, his pace and skill down the right prompting almost continuous volleys from an increasingly frustrated Mourinho on the sidelines.

A free-kick from the Dutchman almost led to an equaliser when it fell to Mueller, only for the German’s snap-shot to be blocked, before a fine curler again brought the best out of Cesar in the Inter goal minutes later.

But, just as in the first half, for all their considered build-up Bayern were always vulnerable on the counter attack, and another moment of Milito magic settled it.

The Argentine – a constant thorn in the Germans’ side – had it all to do when he collected Samuel Eto’s pass on 70 minutes, but did it he did, running at Mark van Buyten, turning the defender brilliantly – though far too easily – before side-footing a sensational 30th goal of his season.

The goal was effectively game, set and match, Bayern’s sting very much drawn and Inter allowed to coast to victory thereafter.

The final whistle, fittingly, prompted a warm embrace between Mourinho and Van Gaal, before the former, after enjoying the celebrations with his team, stalked the Inter end a lone figure, waving deadpanned towards the Italian faithful.

However, having beaten the English, Spanish and German champions en route to club football’s most sought-after trophy – his Inter side worthy champions of Europe – few could envy Mourinho his moment.

Inter Milan12 Julio Cesar04 Zanetti06 Lucio13 Maicon25 Samuel26 Chivu yellow card (Stankovic 68)10 Sneijder19 Cambiasso09 Eto’o22 Milito (Materazzi 90+1)27 Pandev (Muntari 79)Substitutes01 Toldo,02 Cordoba,23 Materazzi,05 Stankovic,11 Muntari,17 Mariaga,45 BalotelliRef: HowardWebbAtt: 80,100INTER MILANPossessionBayern Munich 59%Inter Milan 41%Attempts on targetBayern Munich 10Inter Milan 7Attempts off targetBayern Munich 7Inter Milan 2CornersBayern Munich 7Inter Milan 2FoulsBayern Munich 14Inter Milan 10

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One in the eye for custard pie champions

Picture by Martin Cox

Competitors are preparing to clown about in the 43rd world custard pie championships near Maidstone.

Teams at the event in the village of Coxheath are given maximum points for throwing a pie squarely into their opponents’ faces.

Judges can also award up to five points for the most original and amusing throwing techniques.

The championships were started in 1967 by councillor Mike Fitzgerald to help raise funds to build a village hall.

The event, which was inspired by the Charlie Chaplin comedy, Behind The Screen, starts at 1445 BST.

This article is from the BBC News website. © British Broadcasting Corporation, The BBC is not responsible for the content of external internet sites.

Man wounded in festival shoot-out

One man was injured as two groups shot at each other during a festival in an east London park.

The shooting happened at 1530 BST in London Fields, Hackney, at the junction of Shrubland Road and Forest Road.

The wounded man has sustained life-threatening injuries, the Metropolitan Police said.

A BBC journalist who saw the incident said there was an outbreak of shooting between two groups. The injured man was shot in the stomach.

No arrests have been made. Paramedics and police officers remain at the scene.

Hundreds of families had gathered for the day-long festival, organised by Hackney Council, to preview other events to be held in the borough’s parks.

The BBC journalist said he saw several men on a bench get up and run.

They were followed by another group of men and shots were exchanged.

This article is from the BBC News website. © British Broadcasting Corporation, The BBC is not responsible for the content of external internet sites.