The bill proposes allowing licensing boards to raise the age for off-sales purchases to 21 Scottish government plans which could see under 21s banned from buying alcohol from off-sales are set to be rejected by MSPs.
Labour, the Tories, and the Lib Dems said the measures discriminated against young people.
Opposition MSPs on Holyrood’s health committee will combine to strike the measure from the SNP’s Alcohol Bill.
The committee has already voted to remove government plans for a minimum price for each unit of alcohol.
The Scottish government brought forward its bill, saying radical action was needed to tackle Scotland’s historic alcohol problems.
Other measures in the bill include a ban on drink promotions, a retailers’ social responsibility fee and tighter proof of age rules.
It also proposed allowing local licensing boards to raise the age at which off-sale purchases could be made, from 18 to 21.
Under the plans, 18-year-olds would still be able to drink in pubs and clubs.
But opposition parties will back an amendment from Labour MSP Richard Simpson to remove the age-raising provisions.
The move has been backed by the National Union of Students.
NUS Scotland President Liam Burns, said: “It seems totally wrong that someone could vote, pay taxes and bring up a family but not buy alcohol for their own home.”
If the measure is removed, the SNP has the option of trying to re-insert it when parliament debates the Alcohol Bill at its third and final stage.
The government has already said it will take a similar course of action with its plan to set a minimum price per unit of alcohol.
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