what’s the meaning of “ERR_ACCESS_DENIED” in chrome?

I have some issue about “ERR_ACCESS_DENIED”, I deploy a website server, and there is a upload file function，but recently it doesn’t work, I checked the chrome console, in Network tab, it shows “(failed)net::ERR_ACCESS_DENIED”, I don’t known why because I do not change my code recently, and the request didn’t arrive my background program which is a java web process(debug breakpoint), even the nginx, so what’s ths meaning of “ERR_ACCESS_DENIED”, Does this have anything to do with the chrome version? please give me some help