The European Commission ordered RBS to sell its insurance arm by 2013 More than 600 jobs are to be cut at the Direct Line insurance firm owned by the Royal Bank of Scotland.
Workers at the Atlantic Quay offices in Glasgow have been called to a meeting later to be told the news.
The bank announced in May that 2,000 jobs would go at its insurance division, which it was ordered to sell by the European Commission by 2013.
The Atlantic Quay office is to close within three years although more jobs will be created elsewhere in the city.
A statement from the bank said: "We announced in May that we were looking to consolidate our UK office network as part of our plans to achieve efficiencies across our Insurance business as we prepare it for sale as mandated by the EU.
"However we do not comment on speculation and have a commitment to our staff that we will always tell them first if we are announcing any changes that affect them."
This article is from the BBC News website. © British Broadcasting Corporation, The BBC is not responsible for the content of external internet sites.